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I have a doctors letter and prescription information if needed. Provide documentation when requested, but dont volunteer excessive medical details
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Starting assumptions for a hypothetical 220 lb (100 kg) patient: Baseline BMR: approximately 2,000 calories/day Total daily expenditure (TDEE): approximately 2,400 calories/day (sedentary) Retatrutide effects on the energy equation: Caloric intake reduction: 25-35% (based on food intake data) = 600-840 fewer calories consumed Estimated thermogenic increase: 5-10% of BMR = 100-200 additional calories burned Combined daily deficit: 700-1,040 calories At 48 weeks, this deficit accounts for approximately 54-80 pounds of weight loss, aligning with observed clinical results
It is interesting to speculate as to whether progesterone-only contraceptives could indirectly alter insulin sensitivity (64, 65)
There are two well-known incretin hormones: gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1)
Seek urgent same-day medical attention if you develop severe, persistent upper abdominal pain (especially if radiating to the back) with vomiting, as these could be symptoms of acute pancreatitisa rare but serious adverse effect noted in the Wegovy SmPC
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