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Metformin typically lowers A1C by 1-1.5% while Retatrutide shows reductions over 2%

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Common side effects reported in clinical trials include nausea, constipation, diarrhea, vomiting, and abdominal pain

they used this approach to remove diabetes as a confounder and isolate the effects of the drug

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The intersection of these agents with the central nervous system provides a new lens for conceptualizing bipolar disorders complexity, highlighting the need for personalized, multi-faceted care