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Principal component analysis (PCA) was used as an unsupervised approach to explore global metabolic variation between the two groups

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This intramolecular salt bridge is present on the same face of the peptide -helix in the active state AMYR structures and rotamers of both residues constrain each other with their sidechains located close to ECL2 of the CTR protomer (Fig

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Most patients will need to rest for about a week before returning to normal activities such as work or school