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Enhancing metformin effects by adding gut microbiota modulators to ameliorate the metabolic status of obese, insulin-resistant hosts
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Normal dermal fibroblasts were seeded into a 96-well cell culture plate and have been grown to confluence in high glucose media, supplemented with 10% fetal calf serum for around 3 days
Each line was initially differentiated to DE under the 4 conditions used in the initial EP screen, and after DE induction the cells were then differentiated to smHLCs 11
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