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Electrolyte depletion is more pronounced on higher doses

Klicek et al., 2013

Individual factors also play a significant role in determining who experiences bloating and to what degree

110 Treatment with 1,500 mg curcumin per day for 12 weeks was also shown to upregulate expression of a PPAR- activator molecule and improve markers of oxidative stress more than placebo in a controlled trial in 72 women with PCOS