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Inhibition of IDH1 also sensitized CCNE1-driven tumors to olaparib in vivo ( Fig
The condition must be confirmed by genetic testing demonstrating variants in POMC, PCSK1, or LEPR genes that are interpreted as pathogenic, likely pathogenic, or of a variant of uncertain significance (VUS)
PMID: 27847966 | doi:10.1007/s00109-016-1488-y Chang CH et al
The current NICE guideline on obesity management (CG189 and its updates) emphasises the importance of dietary counselling as part of any pharmacological weight management programme
If you have thyroid disease, communication with your primary care doctor or endocrinologist is recommended so they can monitor TSH and adjust thyroid medication if needed
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