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Common side effects of tirzepatide include nausea, diarrhea, and decreased appetite, similar to semaglutide
& Bjorkman, P
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Biochem J 440(3):385395 Hassan NF et al (2024) The potential role of Tirzepatide as adjuvant therapy in countering colistin-induced nephro and neurotoxicity in rats via modulation of PI3K/p-Akt/GSK3-/NF-kB p65 hub, shielding against oxidative and endoplasmic reticulum stress, and activation of p-CREB/BDNF/TrkB cascade
In clinical trials, approximately 70% of participants reportedly exhibited adverse events, primarily gastrointestinal symptoms, such as diarrhea and nausea
The primary study endpoint was reduction in hemoglobin A 1c over the course of 26 weeks
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