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Additionally, the gastrointestinal side effects of tirzepatide (nausea, vomiting, diarrhea) can cause volume depletion leading to low blood pressure, especially in patients taking diuretics or other antihypertensive medications
Malabsorption Syndromes Orlistat is not recommended for people who have malabsorption syndromes, a condition where the body cannot properly absorb nutrients
It can improve blood sugar control for people with diabetes, and it has been shown to help with weight loss in those who struggle to lose weight through diet and exercise
SadowskaAVerbraeckenJDarquennesKDe BackerW
(2022) NHS [accessed 15 January 2026] Tirzepatide for managing overweight and obesity
There have, however, been anecdotal reports of patients who stop taking one of these medications because their insurance stops covering it or they switch to a new insurance company (say, due to a job change) and can no longer get coverage
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