Another point to keep in mind is that most patients will not have any weight loss during the first 4-5 weeks as you become accustomed to the medication, prior to increasing your dose
This delay can cause food to stay in the stomach longer, leading to increased pressure on the lower esophageal sphincter (LES), the muscle that keeps stomach acid from moving up into the esophagus
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The article also says anyone experiencing nausea, vomiting, or gastrointestinal distress should report those symptoms to their provider rather than pressing forward, and it recommends regular bloodwork covering lipids, liver function, and kidney function to keep the process safe