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One of the frequent epigenetic alterations in hepatocellular carcinoma (HCC) is hypermethylation of the promoters of the Secreted Frizzled-Related Protein (SFRP) gene family, which is a key component in the regulation of the Wnt/ -catenin signaling pathway

While sedated under ether anesthesia, deep partial skin thickness burns were induced on the back of each test subject through the method of control burning