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The synergy between the two pathways is what makes the combination dosing more efficient per unit of compound

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Thyroid C-Cell Tumors: In mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

**** Epinephrine (adrenaline): Not prohibited in local administration, e.g