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ROS generation increases when any key enzyme deficiency or inhibited, while high levels of cumulative ROS cause ferroptosis
GSH also conjugates electrophilic xenobiotics for elimination and has been linked to activation of the Nrf2/HO-1 cytoprotective pathway
Anti-Aging Properties By neutralizing free radicals, glutathione reduces the oxidative damage that contributes to skin aging
10.1016/j.tibs.2006.11.006 Trends Biochem
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