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Nature Medicine -1

It influences glucose and lipid metabolism, modulates inflammatory responses, and impacts vascular endothelial function, playing a role in cardiovascular diseases

The decision is individualized: Pregnancy, breastfeeding, or planning pregnancy within the next two months

Novo Nordisk reported the results from the STEP 1 extension trial on the impact of treatment withdrawal, which found that one year after withdrawal of once-weekly subcutaneous semaglutide 2.4 mg and lifestyle intervention, participants regained two-thirds of their prior weight loss