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Multiple randomized trials and meta-analyses suggest that glutamine supplementation may reduce the incidence or severity of high-grade oral mucositis, although findings are heterogeneous and not all studies demonstrate benefit
Moreover, GLP-1 injections undergo rigorous FDA testing and require medical supervision , ensuring safety and efficacy that patches, sold as supplements, cannot match
Additionally, studies indicate that the absence of GLP-1R signaling in GLP-1R / mice impairs proliferative responses, resulting in increased infiltration of immune cells, including neutrophils and T cells [12, 145]
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