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10.1104/pp.125.4.2164 165 VuilleumierS
Recent research indicates that while these drugs significantly reduce body weight and adiposity, fat-free mass lost accounts for 25-40% of the total weight lost during therapy, raising concerns about muscle loss, which is vital for overall health and physical function
Also, rotating injection sites prevents tissue irritation
Because of its versatility the Economist described the drug behaved 'like a molecular Swiss Army knife' (Economist)
Nutritional status is another consideration
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