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Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: July 11, 2026 The short answer is yes, a little, but not the way the ads promise
But the rest of the road is unpaved
Patients who make it through dose escalation and reach their maintenance dose tend to tolerate the medication well for the remainder of the treatment period
Seek medical advice if persistent sleep problems, neurological symptoms, or mood changes occur after starting B12 supplementation
While the overall risk for serious eye problems appears low, baseline and regular eye exams remain essential
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