At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues
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The discrepancy in the reports of p53 expression in keloids 5,26,27 suggests that the regulatory functions of p53 in keloid fibroblasts depends on activities rather than expression levels of p53
Collectively, AS-IV appears to mitigate CKD progression through multi-faceted regulation of mitochondrial homeostasis
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