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Glutathione s-transferase variants in a brazilian population [PMID: 19258736] Laboratory literature summary: Glutathione s-transferase variants in a brazilian population
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In patients with Parkinsons disease on levodopa monotherapy, vitamin B supplementation can increase peripheral levodopa metabolism and thus reduce the amount of levodopa reaching the central nervous system, worsening symptom control
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The results reveal a deficiency in Vitamin B12
For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia
