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Liver and kidney markers are reasonable to track in extended high-dose protocols
Para el manejo del peso, los estudios clnicos han demostrado prdidas promedio del 15% del peso corporal inicial con semaglutida 2.4 mg (Wegovy) y hasta 20% con tirzepatida (Zepbound) en algunos pacientes
Current recommendations from the American Society for Metabolic and Bariatric Surgery and the Endocrine Society support considering these agents as part of comprehensive management when lifestyle modifications prove insufficient and specific clinical criteria are met
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While the trial provides strong evidence for the drugs utility, the researchers and outside experts acknowledge several limitations
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