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Glutathione peroxidase-1, an intracellular antioxidant enzyme, also works hand in hand with GSH by transforming hydrogen peroxide into water
For example, rates of nausea in incretin mimetic trials typically range from ~15% to 22% and discontinuation due to AEs range from ~3% to 8%
*Correspondence: Yan-Ru Liu, [email protected]
E.OfverstedtL.-G.et al (2006)
This activation potentially promotes the translocation of GLUT4, a major glucose transporter, to the cell surface, thus facilitating glucose entry into cells
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