doi:10.1161/CIRCULATIONAHA.115.017719 Perkovic V, Tuttle KR, Rossing P, et al
Figure 1: A metabolic use-case comprehensive patient journey view with taXonomy Pathways In clinical trials, GLP-1 drugs showed high adherence (over 85% of patients stayed on therapy), yet real-world use tells a different story: one large study found only 32% of obese patients remained on a GLP-1 therapy after one year, with just 27% meeting standard adherence thresholds
doi: 10.1080/01635581.2022.2115082 77 ShenFCaiWSLiJLFengZCaoJXuB
They can also instigate a sense of satiety, leading to weight reduction and improved glucose regulation
Novo Nordisk finished January-September 2025 with DKK 95.264 billion ($14.907 billion) for semaglutide in adult type 2 diabetes (marketed as Ozempic ), up only 10% from DKK 86.489 billion ($13.533 billion) in January-September 2024
People update their wardrobes