Self-prescribing B12 injections for weight loss purposes is not supported by clinical evidence and may delay diagnosis of underlying conditions contributing to weight concerns or low energy levels
58 Phase 2a trial of GSBR-1290 (120mg) in 40 healthy obese volunteers over 8 weeks demonstrated a significant reduction in BW (120 mg: -4.74%
Manufacturers will then owe money back to CMS for the difference between the WAC and the negotiated $245 net price
Egecioglu et al., 2013b
During the Treatment: An IV line is set up and connected to the saline solution
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, Hruban RH, Iacobuzio-Donahue C, Kern SE, Blair IA, Tuveson DA