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Nat Commun 13(1):92 Laurindo LF, Barbalho SM, Guiguer EL et al (2022) GLP-1a: going beyond traditional use
Krupashankar DS, Somani VK, Kohli M, Sharad J, Ganjoo A, Kandhari S
Regulation of mitochondrial dehydrogenases by calcium ions
Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]
The company has utilized a combination of compound patents, method-of-use patents, and device patents to create an IP fortress that extends well beyond the molecules original 20-year term
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