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Kinetic and X-ray crystallographic studies

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Sep 2008;45(3):131-141

The accumulation of lipids enhances the expression of the scavenger receptor CD36, which has been shown to suppress the effector functions of CD8 + T cells, playing a critical role in tumor immune evasion

Patients who maintain their results beyond 12 weeks are those who adjusted caloric intake downward as weight decreased, incorporated refeed days to manage leptin suppression, and understood that the injections support the process but don't override thermodynamics