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A 2025 narrative review in Current Reviews in Musculoskeletal Medicine identified only three published human studies: Lee & Padgett (2021) on knee pain (n=16), Lee et al
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Choosing sites with a reasonable depth of subcutaneous tissue, and ensuring adequate injection depth into the subcutaneous layer rather than intradermally or intramuscularly, reduces direct nerve stimulation and the associated discomfort
Como el resto de la clase, su evidencia sigue siendo mayormente preclnica
This does not mean injections are unnecessary it means they are not automatically superior for every patient
We want to align with Type 3 or 4
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