Glutathione therapy typically involves intravenous (IV) administration of glutathione, often combined with vitamins and minerals
upregulation of antioxidant enzymes like catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR) glutathione peroxidase (GPx), heme oxygenase, endothelial nitric oxide synthase, and other protective proteins ( In addition to the above biological functions, carnitine also plays an important role in anti-apoptosis and protection of mitochondrial biogenesis and integrity, which are beyond the scope of this study ( Application in Diseases Carnitine, a natural compound closely related to the above-mentioned functions, has recently been found to alter the underlying disease pathology with fewer side effects ( Role of Carnitine in the Pathogenesis of NAFLD and Associated Diseases Carnitine and Multiple Hit Hypothesis in the Pathogenesis of NAFLD The prevalence of NAFLD is increasing at a tremendous rate, currently affecting about 24% of the world's population
Meenakshi-Sundaram, S
Mitochondrial metabolism as a target for cancer therapy
These future directions collectively represent a transformative shift from reactive BP management to proactive redox-based prevention and personalized treatment of hypertensive vascular disease
DNA damage repair: PARP1 consumes NAD+ to detect and repair DNA strand breaks
