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the two large null dementia-prevention trials ( GEM , JAMA 2008 and GuidAge , Lancet Neurology 2012)

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doi: 10.4103/0378-6323.60557

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91 Activation of p53 can disrupt Asp-Asn homeostasis and promote cell senescence and cycle arrest in lymphoma and colorectal tumor models

We adjust buffer systems and enrichment conditions based on matrix type to optimize recovery and specificity