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Eggers test was used to assess publication bias
Compared to Fe2+, the polyphenol ligands significantly stabilized Fe3+
In the SUSTAIN 6 trial, over 3,297 patients with type 2 diabetes with established chronic kidney disease and/or cardiovascular disease underwent randomization to semaglutide or placebo and were followed for 2 years resulting in a 26% risk reduction in the combined endpoint of rate of cardiovascular disease, nonfatal myocardial infarction, or nonfatal stroke [47]
On the other hand, another study found that 3-month treatment with NR in a PD mouse model resulted in increased NMN and NAD + metabolism marker NAAD but did not increase NAD + levels 287