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C3/C2 = propionyl-CoA carboxylase (elevated in propionic/methylmalonic acidemia)

Reger MA, Watson GS, Green PS, Wilkinson CW, Baker LD, Cholerton B, et al

Its ability to regulate appetite and slow gastric emptying leads to significant weight loss, often surpassing results seen with other peptides in clinical studies

When looking at the percentage of participants that dropped out of the trial due to adverse effects, 2-6% of patients in the cagrilintide group discontinued treatment early while 7% of the participants receiving liraglutide discontinued treatment early, These findings were in comparison to only 3% of test subjects from the placebo group that discontinued treatment due to adverse events [1]

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As a result, people are less likely to overeat, leading to a reduction in overall calorie intake