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From the docking analysis, the GTs active site can accommodate epothilone properly to facilitate the conjugation via the thiol-epoxide reaction with a binding affinity 8.0 kcal/mol, revealing the favorable interaction with the enzyme binding pocket to form glutathione-epothilone conjugate (12-hydroxy-13-(glutathion-S-yl) Epothilone B)

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Response varies, and treatment should be monitored by a healthcare provider

The SLC4 family of bicarbonate (HCO 3 ) transporters

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