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A specific caution for copper peptides: heat, shaking and incompatible diluents can drive copper to dissociate from the peptide, and loosely bound Cu can generate reactive oxygen species another reason to keep handling gentle and cold [2]
It was originally identified as a fragment derived from a larger protein found in human gastric juice, which sparked early scientific interest due to its unusual stability and biological activity under experimental conditions
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Despite its favorable safety record, researchers should note the possibility of injection-related side effects like inflammation, itching, swelling, or pain at the site of injection
Ritson M, Wheeler-Jones CPD, Stolp HB (2024) Endothelial dysfunction in neurodegenerative disease: is endothelial inflammation an overlooked druggable target
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