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Brello requires a 3-month minimum commitment

13 Another study found that patients with MDD had significantly lower plasma levels of ALC compared to healthy controls, and these levels were inversely correlated with depression severity and duration

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Insurance coverage varies widely, with some plans requiring prior authorization, step therapy (trying cheaper medications first), or denying coverage altogether

Table S2 provides additional details on the instruments used to collect food- and appetite-related metrics for these studies

Zepbound, or tirzepatide in general, while operating under the same mechanism as other GLP-1 drugs, may exhibit subtle differences in its onset of effects due to its formulation