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Half of those with diabetes and 65% of those without diabetes discontinued their treatment within one year.[1] These poor levels of adherence come down to several factors
For example, after 12 months of treatment with once-weekly GLP-1 RAs, a mean weight loss of 3.1 kg (95% CI 3.9, 2.3) was reported for adherent patients, whereas the mean weight loss in poorly adherent patients over the same time frame was 1.1 kg (95% CI 1.8, 0.4)
I have also heard about drugs called DPP4- inhibitors
Lastly, a retrospective cohort study compared post-treatment outcomes for semaglutide and tirzepatide in a population of patients without T2DM
Both medications can cause nausea, vomiting, diarrhea, indigestion, stomach pain, and constipation
In fact, whenever I get into, you know, presenting people with evidence, what they end up defaulting to is, well, I just don't trust science because it can just be
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