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A casecontrol study involving 58 PD patients compared to 20 healthy controls showed that IL-1, TNF-, IL-6, CRP, and IL-12 are increased in PD patients compared to healthy controls (Kim et al
To further support the claim that the model is minimal, we performed a parameter identifiability analysis as detailed in the Methods - Uncertainty estimation section
This makes the Phase most expensive
SLC2A1 (GLUT1) is a central regulator of immunometabolic reprogramming in sepsis and a promising biomarker of disease severity
Ladner KJ, Caligiuri MA, Guttridge DC (2003) Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene products
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