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Recent research suggests that -tocopherol supplementation reduces intracellular iron accumulation, attenuates lipid peroxidation, upregulates GPX4 expression, and restores mitochondrial membrane potential, thereby mitigating hepatotoxicity
If you can tolerate it, your prescriber will increase the dosage by 2.5 mg every 4 weeks
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showed that MTX-induced liver, kidney and heart damage was ameliorated with a flavonoid derivative diosmin (Reference Abdel-Daim, Khalifa and Abushouk47)
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