In other words, you are not only paying for the compound
For example, NAPQI, the toxic metabolite, is primarily the product of CYP2E1 metabolism, and there is evidence that younger children have a relative immaturity in CYP2E1 metabolism, which would substantially reduce the production of this toxic metabolite in infants.7 After birth, CYP2E1 protein expression and activity increases, reaching adult levels by about 1 year of age.7 The ability of the liver to metabolize acetaminophen changes with age owing to differences in activity of these key metabolic pathways
TREM2 variants in Alzheimers disease
Personally, I know through genetic testing that I have the SNP (single nucleotide polymorphism) rs1050450(C;T) on my GPX1 gene which reduces my glutathione peroxidase activity and therefore my ability to combat oxidative stress
doi: 10.4103/0019-5545.196976 5 PittengerCBlochMH
Somewhat lower amounts of lipoyllysine (~0.5 g/g dry wt) have been measured in tomatoes, peas, and Brussels sprouts