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Dangerous Reactions While die-off symptoms are generally manageable, certain signs indicate you should stop treatment and consult a practitioner: Persistent fever above 101F Severe abdominal pain or vomiting Neurological symptoms worsening (e.g., vertigo, severe headaches) Bloody or black stools Symptoms continuing beyond 7 days These may signal an adverse reaction or unrelated health issue that needs immediate attention

Another perspective is that fatty acid synthesis may promote inflammation by facilitating TLR activation (45)

Previously, CFTR expression in adult mouse ISCs has been reported in Sox9 low ISCs, which are enriched with LGR5, showing that CFTR is expressed in crypt-base stem cells where adult ISCs are located and acts as a growth suppressant 100

(PubMed) Speckmann B, Steinbrenner H

Try to limit processed foods, sugary drinks, and excessive amounts of unhealthy fats