Central muscarinic cholinergic activation alters interaction between splenic dendritic cell and CD4+CD25- T cells in experimental colitis
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It occurs in less than 1% of patients and is typically caused by the needle accidentally nicking a small blood vessel under the skin
ARM, especially with tools like mcompass, offers a non-invasive, objective way to assess lower GI function and differentiate between side effects and structural dysfunction
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These systems often deliver antigens and adjuvants or cyclic dinucleotide STING agonists within lipid or polymeric carriers, aiming to enhance dendritic cell uptake, support type I interferon responses and improve the depth of response when combined with checkpoint blockade [76, 77, 81]