The protocol enrolled 670 adults who completed 36 weeks of open-label tirzepatide (achieving a mean weight loss of 20.9%), then randomised them to either continue tirzepatide or switch to placebo for another 52 weeks
Due to such frequent usage, our brains rewire themselves to attend to the device, especially if it is within arms reachmaking it all the more difficult to break away from the dopamine drip it provides
The same dopamine suppression that quiets cravings might flatten mood, reduce motivation, or delete the capacity for joy in someone already prone to depression
Key Points to Keep in Mind Lower-dose maintenance supports metabolic stability rather than aggressive loss
Three months might feel like a long time when youre eager for results, but its actually just the beginning of your Zepbound journey
Stop eating at the first sign of nausea