Without offering a citation for a published paper or sharing any data, Sikirics 2025 review states that this clinical trial found that the drug was safe and well-tolerated in humans
Glucagon is traditionally known as the hormone that raises blood sugar when it drops too low, but it also plays a crucial role in energy expenditure and fat metabolism
Patients were randomized in a 2:1 ratio to either WEGOVY 25 mg tablet or placebo
Many patients report that after losing 1015% of their body weight on semaglutide, their energy levels improve and hypothyroidism symptoms (fatigue, cold intolerance, dry skin) diminish
Is this for human use?+ No
Li welcomed this question, stating that his group was interested in investigating this same topic and that the next steps of their work will be to better characterize these mechanisms that may be resulting in alterations in urinary biochemistry