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Animal research has explored its potential effects on: Stomach ulcers Intestinal injuries Gastrointestinal inflammation Esophageal damage Intestinal anastomoses Fistulas Short-bowel syndrome NSAID-related injury Alcohol-related gastric damage Mucosal integrity A major review described successful healing across multiple experimental gastrointestinal models, including intestinal anastomoses and several types of gastrointestinal fistulas in rats

A search was conducted using databases of EMBASE, PubMed, Scopus, Cochrane Library, and ISI web of Science from inception to February 2019 without limitations in language

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