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The researchers say the results support conducting clinical trials specifically designed to test GLP-1 drugs as addiction treatments, including studies capable of measuring effects on overdose and drug-related death
Clinical impact
1 illustrates the study selection process
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The most significant published data come from a Phase 2 trial published in The New England Journal of Medicine (Jastreboff et al., 2023), which evaluated retatrutide across multiple doses in adults with obesity or overweight
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