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Avoid using lotions, oils, moisturisers, or alcohol-based products on the application site, as these may interfere with patch adhesion or drug absorption
Semaglutide (GLP-1 receptor agonist) improves systemic metabolism, leading to a higher rate of MASH resolution as well as significant fibrosis improvement
However, evidence from the FOURIER (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk) trial did not show a significant risk reduction in stroke with evolocumab within secondary outcome analysis
Dietary interventions provide the foundation and often produce the most dramatic improvements
Seek clinical practice advice for any laboratory work involving injections
Maintenance: 10 mg weekly from Week 13
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