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Abstract Background Glucagon-like peptide-1 (GLP-1) is a crucial incretin hormone secreted by intestinal endocrine L cells

In contrast, Treg cells require a considerable period of time, spanning several days, to invade the brain following the onset of ischemia, and maintain in a significant number for more than one month (71)

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One study reported the presence of GLP-1R on the membrane of human liver cells, which undergoes endocytosis following GLP-1RA stimulation and acts by regulating downstream molecules of insulin signaling

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