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NEWLY REGISTERED TRIALS (3 in last week) PG-102(MG12) Phase II investigating a switch from dulaglutide in patients with type 2 diabetes mellitus (ProGen
They were the ones who actually make the big change here like 5 or 10 years ago
Sales of semaglutide made up 86% of Novos total U.S
The UK medicines regulator, the MHRA, has updated the product information for healthcare professionals and patients regarding the "small risk of severe acute pancreatitis in patients taking GLP-1s." While rare, the sheer scale of GLP-1 use in the UK with one recent study suggesting 1.6 million adults had used them in the last 12 months, and 3.3 million were interested in trying them in the following year makes it important for clinicians and patients to be aware of the warning signs of pancreatitis, said the regulator
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We see the same thing with the association between GLP-1 receptor agonists and macular degeneration, a much more common form of blindness in which people (usually older adults) lose sight at the centre of their vision but can still see around it
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