Higgins V, Asgari S, Hamilton JK, Wolska A, Remaley AT, Hartmann B, et al
Only Wegovy and Saxenda have been approved for use as weight-loss medications by Health Canada
You start at a low dose (typically 0.25mg weekly) and gradually increase over several months until you reach a therapeutic dose
A Medicare GLP-1 Bridge program is reported to begin in July 2026, giving eligible Part D members access to weight-loss medications like Zepbound for a $50 copay per 30-day supply
Wegovy drug interactions: 12 medications that affect semaglutide Ready to take the next step
The full three-way comparison including retatrutide provides additional context for understanding where these medications fall in the broader landscape of metabolic therapeutics