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You should contact your clinician if: Appetite returns sharply Weight increases beyond your agreed maintenance range You regain 5 to 10 pounds Side effects affect eating, hydration, or activity You are considering stopping, restarting, tapering, spacing, or changing GLP-1 medication You feel out of control with cravings or binge episodes You have persistent vomiting, severe abdominal pain, dehydration, or concerning symptoms You are pregnant, planning pregnancy, or have a new diagnosis or medication You need updated lab work, metabolic testing, or nutrition targets The safest maintenance plan is proactive, not reactive

Cardioprotective functions in heart failure Both preclinical and clinical studies have demonstrated beneficial effects of GLP-1 on the failing heart

If diarrhea is severe or persistent, seek medical advice

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This is attributed to its actions on increasing appetite and caloric intake