Ingredients: 6 eggs 1 cup spinach, chopped cup diced bell pepper cup onion, minced Salt, pepper, chili flakes Directions: Whisk eggs, stir in veggies + seasoning
Exendin-4 was purchased from Abcam
Dominguez tends to start people on whichever medication might be most effective for a patient, rather than prescribing a less effective drug first
Preclinical and observational evidence, as well as some small studies, suggested potential benefits of GLP-1 agonists, but this large trial does not confirm clinical efficacy in early Alzheimers. Have the authors taken confounding factors into account
Three situations require modification: Renal impairment (eGFR below 60 mL/min/1.73 m) Tirzepatide is not renally cleared (it's metabolized by proteolysis), so renal impairment doesn't directly affect drug levels
Dysbiosis of the gut microbiota can induce metabolic syndromes, inflammation, and hormone dysregulation 37,38,39,40