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Due to delayed gastric emptying, patients using oral contraceptives should use non-oral or backup contraception for 4 weeks after initiation and each dose escalation
Honest assessment of this alignment helps predict likely satisfaction with outcomes
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The method of synthesis according to claim 1, characterized in that: the acid used for adjusting the pH value of the isoelectric point of the reaction solution in the post-treatment in the step (1) is organic acid or inorganic acid, and the organic acid is any one of trifluoroacetic acid, acetic acid and formic acid
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Conversely, Hantson and coworkers [83] recently reported the case of a 47-year-old epileptic man in whom parenteral VPA therapy was associated with a severe hyperammonaemic encephalopathy (peak ammonia concentration 411 mol/l) without any biological signs of hepatotoxicity
