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Discussion The three trials summarized in TABLE 2 provide consistent evidence that GLP-1 RAs may be an advantageous alternative to prandial insulin as add-on therapy to basal insulin

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And GLP-1R knockdown markedly abolished the effect of liraglutde to modulate the ratio of p-Akt/t-Akt after liraglutide treatment, when compared with both the control and negative control siRNA group (Supplementary Figure S1a and c)

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Low glycaemic index or low glycaemic load diets for overweight and obesity